Product Description

Description:
A florescent yellow coloured, round shaped, biconvex, film coated tablet bisected
on one side with a score line.

Active Pharmaceutical ingredients:
Dapoxetine Hydrochloride 60mg; Tadalafil 20mg

Avg Weight:
306 mg

Diameter/Thickness:
: 9.68 / 4.32 mm

Packing presentation:
Blister in printed Aluminum foil and clear, transparent PVC foil in the following configuration:
Blisters of 10's

Who is this for?

Dapoxetine is a unique, short-acting, selective serotonin reuptake inhibitor (SSRI) which has been clinically proven to be effective in the treatment of PE (Premature ejaculation.) in men aged 18 years or older. Approximately 27-34 percent of men between all age groups get affected by PE. Most of the men ejaculate sooner then they expect. Dapoxetine has been clinically proven to extend the length of time of sexual intercourse by between 200% and 400%.

Tadalafil is used to treat erectile dysfunction of males. It has been found that in many cases, ED and PE are linked, with patients suffering from both disorders.

How does it work?

SSRIs work by blocking a receptor in the brain that absorbs the chemical serotonin. Research suggests that neurotransmitter Serotonin is known to influence mood and behavior. SSRIs block reabsorption (reuptake) of serotonin and this increased serotonin improves mood. SSRIs have the power to mildly influence mood, outlook, and behavior. Although often positive, these same benefits can also be a cause of concern to many people. SSRIs are selective because they affect only serotonin not other neurotransmitters.

Tadalafil does not directly cause an erection of the penis, but it alters the body's response to sexual stimulation by enhancing the effect of the nitric oxide, a chemical that is normally released during stimulation. Nitric oxide causes relaxation of the muscles in the penis, which allows for better blood flow to the penile area.

How long is it effective for?

Dapoxetine hydrochloride has a distinctive pharmacokinetic profile. While other SSRIs take around two weeks or longer to become effective, Dapoxetine hydrochloride reaches its maximum serum concentration, becoming effective in about one hour and being eliminated from the body's system within one to two hours. Twenty-four hours after the treatment, the plasma concentrations are less than five per cent of climax quantity. The conclusion is that this quick passing time through the body makes the drug appropriate for on-demand therapy.

Dapoxetine has a relatively short 1/2 life of 2-3 hours - within this time the concentration of Dapoxetine in the plasma has metabolized to approximately 50% of it's initial concentration. Hence, optimum effect is within 30 mins to 2 hours after taking the medication.

Tadalafil is effective within 30 - 45 mins of ingestion and remains effective for 24 - 36 hours.

How should I take it?

Spier T-Ject60 comes as a tablet to take by mouth with water. In clinical studies, Dapoxetine improved some patients' abilities to delay ejaculation by up to 400%.

T-Ject60 should not be taken more than once a day.

What side effects should I watch for?

Dapoxetine treatment is not without major side effects, however. Clinical studies have shown that these included:

• Nausea in 8.7 percent of men getting low-dose (60mg) and 20.1 percent of men getting high-dose Dapoxetine.
• Headache in 5.9 percent of men getting low-dose and 6.8 percent of men getting high-dose Dapoxetine.
• Diarrhea in 6.8 percent of men getting high-dose Dapoxetine.
• Dizziness in 6.2 percent of men getting high-dose Dapoxetine.

Although side effects from tadalafil are not common, they can occur. Tell your doctor if any of these side effects are severe or do not go away:

• headache
• nausea
• upset stomach
• dizziness or lightheadedness
• flushing (feeling of warmth)
• stuffy or runny nose
• muscle aches
• back pain

If you experience any of the following symptoms, call your doctor immediately:

• rash
• painful erection
• prolonged erection (longer than 4 hours)
• changes in vision
• fainting
• chest pain
• itching or burning during urination

If you become dizzy or nauseated call your doctor right away. You could be having a serious side effect. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. This does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). You should know that sexual activity may be a strain on your heart, especially if you have heart disease. If you have chest pain during sexual activity, call your doctor immediately and avoid sexual activity until your doctor tells you otherwise. Stop using this and get emergency medical help if you have sudden vision loss. Avoid drinking alcohol, which can increase some of the side effects.

When should I be careful taking it?

You should not take T-Ject60 if:

• You are allergic to dapoxetine or lactose, the ingredients of the SPIER T-Ject60 tablet.
• You have heart failure or other serious heart problems such as a heart arrhythmia.
• You have moderate or severe liver problems.

You should also not take T-Ject60 in conjunction with any of the following medicines:

• Meds used to treat depression called "monoamine oxidase inhibitors" (MAOIs)
• Other drugs used to treat depression
• Thioridazine used for schizophrenia
• Lithium, a drug used to treat bipolar disorder (Kerry Katona)
• Linezolid - an antibiotic
• Tryptophan - a sleeping pill
• St John's wort - a herbal medicine
• Tramadol - a strong pain killer
• Drugs used to treat migraines.

You must not take T-Ject60 concurrently with any of the above drugs. In addition, you must stop any of the above drugs a clear fourteen days before starting to take T-Ject60. If you stop using T-Ject60, you will need to wait a clear seven days before starting any of the above medicines.

• Some medicines used to treat fungal infection, including ketoconazole and itraconazole
• Some medicines used to treat HIV, including ritonavir, saquinavir, nelfinavir and atazanavir
• Some medicines used to treat infection, including telithromycin
• Nefazodone - an antidepressant

Do not take T-Ject60 if you are taking any of the above drugs. You should not take T-Ject60 with alcohol, as the effects of alcohol may be amplified, leading to increased risk of fainting or other side effects.

You should also check with your doctor before taking T-Ject60 if:

• You have not been diagnosed with premature ejaculation
• You have ever had any type of mental health problem
• You use recreational drugs
• You have blood clotting problems, kidney problems, epilepsy or dizziness from low blood pressure

Before you start to take and ED or PE medication, your GP should perform a test to ensure that your blood pressure doesn't drop too much when you stand up from lying down.